KEGG   Homo sapiens (human): 9507
Entry
9507              CDS       T01001                                 
Symbol
ADAMTS4, ADAMTS-2, ADAMTS-4, ADMP-1
Name
(RefSeq) ADAM metallopeptidase with thrombospondin type 1 motif 4
  KO
K07764  a disintegrin and metalloproteinase with thrombospondin motifs 4 [EC:3.4.24.82]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    9507 (ADAMTS4)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.82  ADAMTS-4 endopeptidase
     9507 (ADAMTS4)
Peptidases and inhibitors [BR:hsa01002]
 Metallo peptidases
  Family M12: astacin/adamalysin family
   9507 (ADAMTS4)
SSDB
Motif
Pfam: ADAMTS_spacer1 ADAMTS_CR_2 Reprolysin Reprolysin_5 TSP_1 Reprolysin_3 ADAMTS_CR_3 TSP1_spondin Reprolysin_2 TSP1_ADAMTS Reprolysin_4 Pep_M12B_propep
Other DBs
NCBI-GeneID: 9507
NCBI-ProteinID: NP_005090
OMIM: 603876
HGNC: 220
Ensembl: ENSG00000158859
UniProt: O75173
Structure
Position
1:complement(161184302..161199054)
AA seq 837 aa
MSQTGSHPGRGLAGRWLWGAQPCLLLPIVPLSWLVWLLLLLLASLLPSARLASPLPREEE
IVFPEKLNGSVLPGSGAPARLLCRLQAFGETLLLELEQDSGVQVEGLTVQYLGQAPELLG
GAEPGTYLTGTINGDPESVASLHWDGGALLGVLQYRGAELHLQPLEGGTPNSAGGPGAHI
LRRKSPASGQGPMCNVKAPLGSPSPRPRRAKRFASLSRFVETLVVADDKMAAFHGAGLKR
YLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGSGEEGPQVGPSAAQTLRSFCAWQRGLN
TPEDSDPDHFDTAILFTRQDLCGVSTCDTLGMADVGTVCDPARSCAIVEDDGLQSAFTAA
HELGHVFNMLHDNSKPCISLNGPLSTSRHVMAPVMAHVDPEEPWSPCSARFITDFLDNGY
GHCLLDKPEAPLHLPVTFPGKDYDADRQCQLTFGPDSRHCPQLPPPCAALWCSGHLNGHA
MCQTKHSPWADGTPCGPAQACMGGRCLHMDQLQDFNIPQAGGWGPWGPWGDCSRTCGGGV
QFSSRDCTRPVPRNGGKYCEGRRTRFRSCNTEDCPTGSALTFREEQCAAYNHRTDLFKSF
PGPMDWVPRYTGVAPQDQCKLTCQAQALGYYYVLEPRVVDGTPCSPDSSSVCVQGRCIHA
GCDRIIGSKKKFDKCMVCGGDGSGCSKQSGSFRKFRYGYNNVVTIPAGATHILVRQQGNP
GHRSIYLALKLPDGSYALNGEYTLMPSPTDVVLPGAVSLRYSGATAASETLSGHGPLAQP
LTLQVLVAGNPQDTRLRYSFFVPRPTPSTPRPTPQDWLHRRAQILEILRRRPWAGRK
NT seq 2514 nt   +upstreamnt  +downstreamnt
atgtcccagacaggctcgcatcccgggaggggcttggcagggcgctggctgtggggagcc
caaccctgcctcctgctccccattgtgccgctctcctggctggtgtggctgcttctgcta
ctgctggcctctctcctgccctcagcccggctggccagccccctcccccgggaggaggag
atcgtgtttccagagaagctcaacggcagcgtcctgcctggctcgggcgcccctgccagg
ctgttgtgccgcttgcaggcctttggggagacgctgctactagagctggagcaggactcc
ggtgtgcaggtcgaggggctgacagtgcagtacctgggccaggcgcctgagctgctgggt
ggagcagagcctggcacctacctgactggcaccatcaatggagatccggagtcggtggca
tctctgcactgggatgggggagccctgttaggcgtgttacaatatcggggggctgaactc
cacctccagcccctggagggaggcacccctaactctgctgggggacctggggctcacatc
ctacgccggaagagtcctgccagcggtcaaggtcccatgtgcaacgtcaaggctcctctt
ggaagccccagccccagaccccgaagagccaagcgctttgcttcactgagtagatttgtg
gagacactggtggtggcagatgacaagatggccgcattccacggtgcggggctaaagcgc
tacctgctaacagtgatggcagcagcagccaaggccttcaagcacccaagcatccgcaat
cctgtcagcttggtggtgactcggctagtgatcctggggtcaggcgaggaggggccccaa
gtggggcccagtgctgcccagaccctgcgcagcttctgtgcctggcagcggggcctcaac
acccctgaggactcggaccctgaccactttgacacagccattctgtttacccgtcaggac
ctgtgtggagtctccacttgcgacacgctgggtatggctgatgtgggcaccgtctgtgac
ccggctcggagctgtgccattgtggaggatgatgggctccagtcagccttcactgctgct
catgaactgggtcatgtcttcaacatgctccatgacaactccaagccatgcatcagtttg
aatgggcctttgagcacctctcgccatgtcatggcccctgtgatggctcatgtggatcct
gaggagccctggtccccctgcagtgcccgcttcatcactgacttcctggacaatggctat
gggcactgtctcttagacaaaccagaggctccattgcatctgcctgtgactttccctggc
aaggactatgatgctgaccgccagtgccagctgaccttcgggcccgactcacgccattgt
ccacagctgccgccgccctgtgctgccctctggtgctctggccacctcaatggccatgcc
atgtgccagaccaaacactcgccctgggccgatggcacaccctgcgggcccgcacaggcc
tgcatgggtggtcgctgcctccacatggaccagctccaggacttcaatattccacaggct
ggtggctggggtccttggggaccatggggtgactgctctcggacctgtgggggtggtgtc
cagttctcctcccgagactgcacgaggcctgtcccccggaatggtggcaagtactgtgag
ggccgccgtacccgcttccgctcctgcaacactgaggactgcccaactggctcagccctg
accttccgcgaggagcagtgtgctgcctacaaccaccgcaccgacctcttcaagagcttc
ccagggcccatggactgggttcctcgctacacaggcgtggccccccaggaccagtgcaaa
ctcacctgccaggcccaggcactgggctactactatgtgctggagccacgggtggtagat
gggaccccctgttccccggacagctcctcggtctgtgtccagggccgatgcatccatgct
ggctgtgatcgcatcattggctccaagaagaagtttgacaagtgcatggtgtgcggaggg
gacggttctggttgcagcaagcagtcaggctccttcaggaaattcaggtacggatacaac
aatgtggtcactatccccgcgggggccacccacattcttgtccggcagcagggaaaccct
ggccaccggagcatctacttggccctgaagctgccagatggctcctatgccctcaatggt
gaatacacgctgatgccctcccccacagatgtggtactgcctggggcagtcagcttgcgc
tacagcggggccactgcagcctcagagacactgtcaggccatgggccactggcccagcct
ttgacactgcaagtcctagtggctggcaacccccaggacacacgcctccgatacagcttc
ttcgtgccccggccgaccccttcaacgccacgccccactccccaggactggctgcaccga
agagcacagattctggagatccttcggcggcgcccctgggcgggcaggaaataa

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Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (26)   
   RefSeq(nuc) (4)   
   GenBank (11)   
   EMBL (11)   
3D Structure (5)   
   PDB (5)   
Protein domain (12)   
   Pfam (12)   
All databases (71)   

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